Endocrine Abstracts

Introduction: The diffuse large B-cell lymphoma (DLBCL) is known as one of the most common lymphoma worldwide with the prevalence of 25 % of all of non-Hodgkin lymphoma cases [1], but it is very rearly observed in thyroid. Around 30 % of Clinical cases of the DLBCL appear from extranodal organs, the prognosis depends on the site of origin [2].Case: A 18-year-old man was admitted to endocrinologist, complaining with a palpable nodule in the front neck for...

Introduction: Maturity-onset diabetes of the young (MODY) is a form of diabetes mellitus transmitted by an autosomal dominant mode of inheritance, usually diagnosed before the age of 25 years. Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease, particularly closely related with insulin resistance and type 2 diabetes mellitus. MODY and NAFLD combination has rarely been described in the literature.Case: A 25-year-old women was admitted to...

Introduction: De Quervain’s Thyroiditis (DQT) is a self-restriction inflammatory disease of the thyroid gland that presents severe pain localized in the neck. But few cases of a painful variant of Hashimoto’s thyroiditis (HT) have been described as well. Thyroid ultrasound (US) may reveal in homogeneous hypoechoic pattern in both conditions.Case: A 51-year old woman was admitted to the Hospital of Lithuanian University of Health Sciences, Kauno...

Introduction: Follicular thyroid carcinoma (FTC) is the second most common thyroid tumor and accounts for about 5-10 % of all thyroid cancers. As FTC often retains the ability to concentrate radioactive iodine (I131), tumor may be responsive to I131 therapy. However, about 60-70 % of all metastatic thyroid cancers are resistant to I131 and has a poor prognosis with 10-year survival rate of 10 % and the average life expectancy 3-5 years after di...

Introduction: Grave’s disease is frequently associated with cytopenia. Pancytopenia, however, is rare. Thyroid hormones have a direct effect on myocardial contractility and left ventricle (LV) diastolic function. Only less than 1% of the patients with hyperthyroidism develop cardiomyopathy with impaired left ventricular systolic function.Case: A 51-year old woman was admitted to the Hospital of Lithuanian University of Health Sciences, Kaunas clinic...

Hashimoto encephalopathy (HE) is a rare and steroid responsive encephalopathy associated with autoimmune thyroiditis (1). Patients with Hashimoto encephalopathy may present with a variety of neuropsychiatric signs (2). 68-year old woman was admitted to the Neurology Department, of Hospital of Lithuanian University of Health Sciences, Kauno klinikos (HLUHS KK), due to disorder of consciousness of uncertain aetiology in August 2016. The signs of motor dysfunction, generalized ri...

Despite that the thyroid gland is one of the most vascular organs of the body but thyroid gland is an uncommon site for metastasis [1]. It represents less than 4% of thyroid malignancy in clinical and surgical studies [2, 3]. 58-year-old male, a prior smoker, was diagnosed with nonsmall cell lung cancer T4N3M1 St IV, histopathological findings - infiltrative adenocarcinoma, G1. About eight months he was treated with chemotherapy. At the beginning of the disease, the patient wa...

Introduction: Women with Turner syndrome (TS) are known to be at risk of decreased BMD (dBMD). Sex hormone replacement therapy is crucial to ensure the proper BMD formation, although the dBMD remains a problem in TS.Aim: To investigate the prevalence of decreased bone mineralization and it’s association with hormone levels in TS.Subjects: Women with geneticaly confirmed TS aged ≥ 18 year.Methods: T...

Introduction: Parathyroid carcinoma (PC) is an extremely rare, aggressive and life-threatening form of primary hyperparathyroidism (pHPT). PC accounts for less than 1% of cases of pHPT, predominantly diagnosed in the fifth or sixth decades of life. Most parathyroid carcinomas are diagnosed after surgery.Case description: A 51-year old man was admitted to the Hospital of Lithuanian University of Health Sciences, Kaunas clinics due to leg pain and general ...

Introduction: Multiple Endocrine Neoplasia Type 1 (MEN1) is a rare, autosomal dominantly inherited syndrome that causes tumors of the endocrine glands [1]. This syndrome is most commonly associated with neuroendocrine tumors of the parathyroid glands, pituitary gland and pancreas [2].Case: A 30-year-old woman was admitted to the Hospital of Lithuanian University of Health Sciences, Kaunas Clinics for unconsciousness and significant hypoglycaemia: 1.0 - 3...